Pings
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Answer Accepted 25 Answers 3 Votes
Does the number of unread emails correlate with blood pressure?
The hypothesis is simple: as unread emails increase, so does stress — and potentially blood pressure. Yes, it’s a light-hearted question, but it taps into a real intersection of digital life and mental/physical health. With email overload being a known contributor to workplace burnout, this research could highlight a simple, visible marker of digital stress, making people’s blood boil.
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Answer Accepted 9 Answers 2 Votes
How do you balance privacy and public health in a pandemic?
Digital contact tracing involves a level of surveillance that could make a lot of people uncomfortable, especially given the involvement of large technology companies with spotty records on privacy. However, contract tracing represents one of the most potent methods for combating the pandemic and is only useful if implemented on a wide scale. How do we balance privacy and public health in these times?
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Answer Accepted 18 Answers 22 Votes
Could salary be used as a surrogate for smoking when sample data are lacking?
In epidemiology cohort studies, information on smoking status is often times lacking for the study sample, which makes it challenging to characterize the effects of other risk factors on endpoints that are causally related to smoking (e.g., lung cancer mortality). Given the strong inverse reported for smoking and income, could salary be used as a surrogate for smoking when direct data are lacking? or would potential relationships between salary other risk factors (e.g., health care access)...
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Answer Accepted 32 Answers 24 Votes
To what extent can AI be used in scientific writing?
Routine aspects of inspection and considerations include, but not limited to: Obtaining the research question and hypothesis, choosing statistical analytic approaches and methods, data Interpretation, English editing, content Generation, drawing conclusions, etc. These are just several aspects, however, the potential hazards include the risk of bias, uniform tone in writing, lack of creativity, etc. Although with supervised use all these aspects can be partially controlled, to what extend do...
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Answer Accepted 25 Answers 20 Votes
AI for academic writing: friend or foe?
Given the increasing availability of AI writing tools, how can academic institutions ensure the responsible use of these technologies while maintaining the integrity of research and scholarship?
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Answer Accepted 8 Answers 0 Votes
What is the relationship between free radicals and the inflammation process during Chronic diseases?
OxInflammation process is a complex and systemic event that occurs after cellular and tissue injury. The knowledge about both processes is that they coexist, but already known that possibly the inflammatory response is responsible for the generation of a pro-oxidative environment due to the production of Free radicals and Reactive Oxygen species (ROS), especially in chronic diseases. In normal tissue occurs the activation of efficient machinery able to control the oxidative stress, however,...
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Answer Accepted 2 Answers 1 Vote
Why we often observe quite different circadian rhythms, for example, for two plants growing in absolutely identical conditions?
Why we often observe quite different circadian rhythms, for example, for two plants growing in absolutely identical conditions?
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Answer Accepted 1 Answer 0 Votes
For me-too medical devices, on what basis should manufacturers choose biological tests to conduct?
Manufacturers producing a me-too medical device intended for implantation in the human body, conducting a full biocompatibility study including implantation effect that takes more than one year does not seem logical. With the availability of a reference medical device of the same material & intended use, how can the manufacturer choose the required biological tests?
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Answer Accepted 4 Answers 0 Votes
What is the best way to deplete resident macrophages in the heart?
I am planning studies that require depleting resident macrophages in the heart in a mouse model of myocardial infarction. There are multiple strategies including Csf1r and CD163 antibodies. What is the most specific and effective way to deplete resident cardiac macrophages?
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Answer Accepted 1 Answer 1 Vote
How the drug dosing space and therapeutic level in term of MTD may best be correlated with pharmacokinetics and body metabolic rate in the subject to gain best possible impact and to minimize the toxicity.
when we recommend the dose of antibiotics like oxytetracycline in animals we usually take into consideration the recommended dose on the label but most of the time the therapeutic effect may not be obtained as suspected. As physician we recommend little bit high dose of the drug in some animals for best results which becomes beyond the regulation authorities to justify. Is it possible to recommend the dosing space or dose of the drug flexible including some criteria of considering BMR of the...
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