Pings
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2 Answers 0 Votes
What health-based guidance values have been set by regulatory agencies for thallium, other than the USEPA reference dose for drinking water (2 micrograms/litre)?
I am trying to find what HBGVs have been set for thallium. The only one I have been able to find is the USEPA RfD for drinking water. My particular interest is whether any regulatory agency has set a HBGV for thallium exposure in the diet.
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6 Answers 0 Votes
How can medical microrobots improve our awareness regarding the diagnosis and treatment of diseases?
How can medical microrobots improve our awareness regarding the diagnosis and treatment of diseases?
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5 Answers 0 Votes
What threshold of urinary cadmium (Cd-U) is currently considered indicative of early renal tubular dysfunction in exposed adult populations?
I am conducting a study on chronic environmental cadmium exposure and its nephrotoxic effects, particularly focusing on early biomarkers of renal tubular damage. Several sources suggest 2 µg/g creatinine as a reference point, but variability exists depending on population, sex, and co-exposure. Could experts clarify which threshold (e.g. 1 µg/g, 2 µg/g, or 5 µg/g creatinine) is most reliable or currently used in risk assessments and clinical practice?
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5 Answers 2 Votes
How can I do a mediation model with one categorical and two continuous variables?
How can I do a mediation model with one categorical and two continuous variables
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1 Answer 0 Votes
How is it possible to say how long the medical implants that are inside the human body will function?
The functional lifespan of implants placed inside the body How we can trust or know that an implant will work for a specific period?
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3 Answers 1 Vote
How many samples do you need to analyze for effective blood plasma products quality control?
A blood bank is set up with a laboratory for the preparation of blood components. Product quality control (e.g. plasma sterility) should be performed. How many samples do you need to analyze for effective control? How do you calculate this number? Does it vary depending on the total number of components produced?
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2 Answers 0 Votes
How does a friccohesity quantum mechanically correlate shear stress and shear rate with surface tension or energy to smoothen systolic and diastolic heart beat with 120/80 mmHg blood pressure?
Pumping large sized food particles with least surface energy, heart needs more energy while for small sized a less. The higher friccohesity predicts small sized food particles with more adherence with blood serum with higher energy moderating shear rate with surface energy.
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6 Answers 1 Vote
I'm wondering, if the EDC such as bisphenol A, was chlorinated during the water treatment process, is the toxicity of formed disinfection by-products (DBPs) from EDCs smaller than the EDCs itself?
Many studies have been conducted on the DBP formation potential of endocrine-disrupting chemicals (EDC), however, the toxicity comparison (before and after the chlorination process) was not comprehensive and limited.
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18 Answers 8 Votes
Is Oxidative Stress sufficient by itself as an indicator and compelling basis for a carcinogenic concern?
Oxidative Stress as a Precursor and Mechanism for Carcinogenicity IARC and others (Smith et al) have identified 10 key characteristics which may be used/considered in the evaluation of carcinogenicity, one of which is oxidative stress. How strong or compelling, if at all, would the data need to be for considering OS as a putative and defensible MOA for carcinogenicity, or would there need to be other tangential/correlative data (e.g., tumors) available. In other words, is OS sufficient by...
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4 Answers 3 Votes
How do you call an outcome if you have multiple endpoints to investigate it?
Hello, When you want to investigate exacerbations (outcome of interest) in asthma, you can measure: 1) the incidence rate in the last year (i.e. mean numbers of exacerbations in the last year in your total population); 2) the frequency of patients reporting one exacerbation in the last year; 3) the time-to-1st-exacerbation within the last year. So you have 3 different endpoints to explore the same outcome. Could you please help me in finding the technical term to define this property of the...
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