Pings
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3 Answers 0 Votes
What are recent machanism of actions, minmum duration of years of heat exposure and minimum temperature required for various heat induced skin cancers, also opnion for Kangri Cancer to be answered
There are various heat induced cancers in world.Duration of exposure,minmum temperature required for inducing pre-malignant changes, sites of cancers are uner review. Mechanism of action is important in these cases Anyone having more knowledge of mechanism of action for Kangri Cancer or other heat induced cancers
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1 Answer 0 Votes
How does friccohesity chemistry act as global physicochemical property with quantum mechanical activity to nanoformulate the smart cosmetics, syrups, supplements, lubricants, antiwrinkle creams ?
Currently, the friccohesity measured using survismeter has emerged as global physicochemical property of smart research methodologies for nanoformulations to bring all the ingredients in a most aligned coordination for generating the extra mileage of each ingredient for applications.
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5 Answers 0 Votes
What threshold of urinary cadmium (Cd-U) is currently considered indicative of early renal tubular dysfunction in exposed adult populations?
I am conducting a study on chronic environmental cadmium exposure and its nephrotoxic effects, particularly focusing on early biomarkers of renal tubular damage. Several sources suggest 2 µg/g creatinine as a reference point, but variability exists depending on population, sex, and co-exposure. Could experts clarify which threshold (e.g. 1 µg/g, 2 µg/g, or 5 µg/g creatinine) is most reliable or currently used in risk assessments and clinical practice?
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1 Answer 0 Votes
How is it possible to say how long the medical implants that are inside the human body will function?
The functional lifespan of implants placed inside the body How we can trust or know that an implant will work for a specific period?
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6 Answers 0 Votes
In an age where the scientific community is often seen as a guarantor and where short-termist policies are the norm, is there still a place for independent research ?
Calls for projects are becoming increasingly time-consuming, with researchers facing intense competition for funding, which is monopolising ancillary services, consultants and even lobbyists. Budgets allocated to research are determined by priorities that vary according to political choices, the coherence of which can legitimately be questioned. All too often, announced policies reflect subjective choices based on unfounded presuppositions, or even deny established scientific facts....
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5 Answers 1 Vote
What is the LOD of polycyclic aromatic hydrocarbons (PAHs)? what is it`s importance in estimation of the hazardous effect of exposure to PAHs?
please explain LOD of PAHs and it`s importance in toxicology
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34 Answers 5 Votes
How to address global food inequity and inequality?
Global food inequity and inequality, which manifests in a situation whereby more than one (out of seven) billion people are hungry, while two billion people eat too much wrong food, can be addressed by: A. The development of accessible rural financial markets (productive credit and consumption credit). B. Adopting the appropriate development technological pathway option for food security (traditional agriculture, industrial agriculture or sustainable agriculture). C. Only...
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6 Answers 1 Vote
I'm wondering, if the EDC such as bisphenol A, was chlorinated during the water treatment process, is the toxicity of formed disinfection by-products (DBPs) from EDCs smaller than the EDCs itself?
Many studies have been conducted on the DBP formation potential of endocrine-disrupting chemicals (EDC), however, the toxicity comparison (before and after the chlorination process) was not comprehensive and limited.
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18 Answers 8 Votes
Is Oxidative Stress sufficient by itself as an indicator and compelling basis for a carcinogenic concern?
Oxidative Stress as a Precursor and Mechanism for Carcinogenicity IARC and others (Smith et al) have identified 10 key characteristics which may be used/considered in the evaluation of carcinogenicity, one of which is oxidative stress. How strong or compelling, if at all, would the data need to be for considering OS as a putative and defensible MOA for carcinogenicity, or would there need to be other tangential/correlative data (e.g., tumors) available. In other words, is OS sufficient by...
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3 Answers 1 Vote
Is important researching the relation between obesogenicity with the space of the cities? How reasons do you give to assess this issue?
Several authors, such as Downs et al. (2020), Mendes et al. (2022); Recine et al.(2022), and Story et al. (2008) address obesity as part of the pandemic frameworks that make up the global obesity/malnutrition syndemic, aggravated by climate change caused by anthropogenic causes. This framework is structured to characterize, then, biological, social and economic interactions of the population, directing to different comorbidities frameworks. Those authors, however, point out that the concept...
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