Pings
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9 Answers 13 Votes
Can pesticides penetrate into fruits and vegetables as well as on their surface? Is it possible to completely remove pesticide residue?
Can pesticides penetrate not only the outside but also the inside of vegetables and fruits? How to remove pesticide residue from the surface? Is it possible to completely remove pesticide residue?
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4 Answers 0 Votes
What threshold of urinary cadmium (Cd-U) is currently considered indicative of early renal tubular dysfunction in exposed adult populations?
I am conducting a study on chronic environmental cadmium exposure and its nephrotoxic effects, particularly focusing on early biomarkers of renal tubular damage. Several sources suggest 2 µg/g creatinine as a reference point, but variability exists depending on population, sex, and co-exposure. Could experts clarify which threshold (e.g. 1 µg/g, 2 µg/g, or 5 µg/g creatinine) is most reliable or currently used in risk assessments and clinical practice?
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6 Answers 0 Votes
No threshold approach in the risk assessment of genotoxic carcinogen. Is it still well supported by current knowledge of carcinogenesis?
No threshold approach is routinely applied in the risk assessment of genotoxic carcinogens. How this approach is supported by data? Isn´ t it somewhat obsolete?
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3 Answers 0 Votes
How do microplastic particle sizes influence bioaccumulation and toxicity in freshwater ecosystems?
Microplasticsand plastic particles smaller than 5 mm are increasingly found in rivers, lakes, and reservoirs worldwide. Their small size allows them to be ingested by a wide range of aquatic organisms, potentially moving up the food chain. Research suggests that particle size may influence how these plastics are taken up, accumulate in tissues, and cause physiological effects, but the mechanisms are still not well understood. Understanding these size-dependent effects is essential for...
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14 Answers 0 Votes
Should a big research (e.g., PhD) be published as one comprehensive high-impact paper or several smaller, faster publications?
Should a big study perhaps a PhD student’s research be published as one comprehensive, high-impact paper or split into several smaller, focused publications? A single major paper can offer a cohesive, in-depth contribution with broader impact, but may delay dissemination. Multiple smaller papers can communicate findings more quickly and stimulate ongoing research, yet may lack the unified context of a larger work. What choice is the best - having a comprehensive paper in high impact journals...
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5 Answers 2 Votes
When the policy exists to share postprints freely on personal sites, why do researchers often refrain from doing so, and what incentives or constraints drive that hesitation?
There has been extensive discussion about the funding model for research publications. Large publishing houses do not fund research themselves; instead, they charge substantial subscription fees or open-access publishing fees. Keeping articles behind paywalls can impede open science and broad access to knowledge. Nevertheless, many publishers grant authors the right to share postprints of their papers immediately on their non-commercial personal blogs or websites. Despite this permission,...
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16 Answers 1 Vote
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Answer Accepted 9 Answers 2 Votes
How do you balance privacy and public health in a pandemic?
Digital contact tracing involves a level of surveillance that could make a lot of people uncomfortable, especially given the involvement of large technology companies with spotty records on privacy. However, contract tracing represents one of the most potent methods for combating the pandemic and is only useful if implemented on a wide scale. How do we balance privacy and public health in these times?
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6 Answers 1 Vote
I'm wondering, if the EDC such as bisphenol A, was chlorinated during the water treatment process, is the toxicity of formed disinfection by-products (DBPs) from EDCs smaller than the EDCs itself?
Many studies have been conducted on the DBP formation potential of endocrine-disrupting chemicals (EDC), however, the toxicity comparison (before and after the chlorination process) was not comprehensive and limited.
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18 Answers 8 Votes
Is Oxidative Stress sufficient by itself as an indicator and compelling basis for a carcinogenic concern?
Oxidative Stress as a Precursor and Mechanism for Carcinogenicity IARC and others (Smith et al) have identified 10 key characteristics which may be used/considered in the evaluation of carcinogenicity, one of which is oxidative stress. How strong or compelling, if at all, would the data need to be for considering OS as a putative and defensible MOA for carcinogenicity, or would there need to be other tangential/correlative data (e.g., tumors) available. In other words, is OS sufficient by...
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