Pings
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6 Answers 0 Votes
How to examine for power of grip in a patient with weakness?
When we do clinical examination for weakness, power is ascertained by MRC grading. However, for grip, MRC grading cannot be used. Is there any method to examine hand grip power other than using dynamometer
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Answer Accepted 1 Answer 0 Votes
How does STAT3 contribute to intestinal mucosal barrier function, particularly during mucosal repair after injury?
Elucidating the role of STAT3 in intestinal epithelial regeneration and barrier integrity is critical for understanding IBD pathogenesis and tissue recovery. Key aspects include: 1.Epithelial-specific vs. immune-cell STAT3 signaling in wound healingDownstream targets (e.g., mucins, 2.tight junction proteins) mediating barrier protectionContext-dependent effects: protective versus pro-inflammatory roles 3.Insights could inform therapeutic strategies for mucosal healing. Relevant diagrams or...
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10 Answers 1 Vote
Can we consider that epidrugs can constitute a good therapeutic strategy against cancer diseases?
Recently, it has been demonstrated that epigenetic perturbations are mainly involved in cancer development. Can we consider that epidrugs can constitute a good therapeutic strategy against cancer diseases ?
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Answer Accepted 1 Answer 1 Vote
What are the current hot topics in oncology, and where is the future of cell, immune, and small molecule therapies headed?
Beyond established CAR-T and checkpoint inhibitors, what emerging trends (e.g., protein degraders, AI-driven drug discovery, off-the-shelf cell therapies) are shaping the next decade of cancer treatment? Which modalities show the most promise for solid tumors?
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Answer Accepted 1 Answer 0 Votes
What are the current hot topics in the study of critical points during the process of cell mutation and development into tumors? How to conduct in-depth research on the future use of AI?
Tumorigenesis is not a linear accumulation of mutations but rather a dynamic process punctuated by critical transition points—windows during which normal cells cross irreversible thresholds toward dysplasia, carcinoma in situ, and ultimately invasive malignancy. Understanding the molecular and ecological drivers of these “tipping points” is fundamental to early interception and prevention. I would like to ask the cancer biology and computational oncology community: Which specific transition...
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Answer Accepted 8 Answers 9 Votes
Why do qualified researchers from low- and middle-income countries often miss out on international roles despite meeting all requirements and how can they improve their chances?
I’m interested in understanding the hidden barriers and practical steps they can take to strengthen their applications
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Answer Accepted 3 Answers 3 Votes
Are the Government Doctors well paid even after having so much workload?
Even after working non-stop the Physicians at Government Institutes and Hospitals are lowly paid.
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Answer Accepted 2 Answers 0 Votes
Does Yoghurt, Cheese and Milk consumption reduce gut gram negative bacteria and toxic plasma bacterial lipopolysaccharides?
RELEVANT REFERENCES: 1. Sharma, A and IJ Martins. The role of Microbiota in the pathogenesis of Alzheimer’s disease. Acta Scientific Nutritional Health. 7.7 (2023): 108-118. 2. Bacterial Lipopolysaccharides and Neuron Toxicity in Neurodegenerative Diseases. Neurology Research and Surgery. 2018; 1(1): 1-3. 3. Overnutrition Determines LPS Regulation of Mycotoxin Induced Neurotoxicity in Neurodegenerative Diseases. Int J Mol Sci. 201516(12): 29554–29573.
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Answer Accepted 7 Answers 2 Votes
Do you think general physicians or medical doctors might be redundant when AGI is fully developed?
This is a burning topic in medical or clinicians' circles globally as it might have the potential to shake up the medical profession due to the concerted efforts by AI enthusiasts by questioning the relevance of the doctors e.g. general physicians if not all (e.g. medial surgeons or specialists). This may be a challenge for the future healthcare planners and might need a thorough debate. The following reference might give a glimpse and assist while answering for my ping question. Kazzazi F....
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Answer Accepted 2 Answers 0 Votes
Does Yoghurt, Cheese and Milk consumption reduce gut gram negative bacteria and toxic plasma bacterial lipopolysaccharides?
RELEVANT REFERENCES: 1. Sharma, A and IJ Martins. The role of Microbiota in the pathogenesis of Alzheimer’s disease. Acta Scientific Nutritional Health. 7.7 (2023): 108-118. 2. Bacterial Lipopolysaccharides and Neuron Toxicity in Neurodegenerative Diseases. Neurology Research and Surgery. 2018; 1(1): 1-3. 3. Overnutrition Determines LPS Regulation of Mycotoxin Induced Neurotoxicity in Neurodegenerative Diseases. Int J Mol Sci. 201516(12): 29554–29573.
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What is a Ping?
A Ping is a single science-based question. The question comes from a fellow SciPinion Expert who is seeking input from the expert community. All participation in this service (i.e. asking or answering questions) is voluntary and anonymous if you prefer.
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You also receive the satisfaction of helping your fellow experts and supporting the scientific community.