Pings
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Answer Accepted 1 Answer 0 Votes
How does STAT3 contribute to intestinal mucosal barrier function, particularly during mucosal repair after injury?
Elucidating the role of STAT3 in intestinal epithelial regeneration and barrier integrity is critical for understanding IBD pathogenesis and tissue recovery. Key aspects include: 1.Epithelial-specific vs. immune-cell STAT3 signaling in wound healingDownstream targets (e.g., mucins, 2.tight junction proteins) mediating barrier protectionContext-dependent effects: protective versus pro-inflammatory roles 3.Insights could inform therapeutic strategies for mucosal healing. Relevant diagrams or...
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4 Answers 0 Votes
How can medical microrobots improve our awareness regarding the diagnosis and treatment of diseases?
How can medical microrobots improve our awareness regarding the diagnosis and treatment of diseases?
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10 Answers 1 Vote
Can we consider that epidrugs can constitute a good therapeutic strategy against cancer diseases?
Recently, it has been demonstrated that epigenetic perturbations are mainly involved in cancer development. Can we consider that epidrugs can constitute a good therapeutic strategy against cancer diseases ?
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Answer Accepted 1 Answer 1 Vote
What are the current hot topics in oncology, and where is the future of cell, immune, and small molecule therapies headed?
Beyond established CAR-T and checkpoint inhibitors, what emerging trends (e.g., protein degraders, AI-driven drug discovery, off-the-shelf cell therapies) are shaping the next decade of cancer treatment? Which modalities show the most promise for solid tumors?
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Answer Accepted 1 Answer 0 Votes
What are the current hot topics in the study of critical points during the process of cell mutation and development into tumors? How to conduct in-depth research on the future use of AI?
Tumorigenesis is not a linear accumulation of mutations but rather a dynamic process punctuated by critical transition points—windows during which normal cells cross irreversible thresholds toward dysplasia, carcinoma in situ, and ultimately invasive malignancy. Understanding the molecular and ecological drivers of these “tipping points” is fundamental to early interception and prevention. I would like to ask the cancer biology and computational oncology community: Which specific transition...
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1 Answer 0 Votes
How is it possible to say how long the medical implants that are inside the human body will function?
The functional lifespan of implants placed inside the body How we can trust or know that an implant will work for a specific period?
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Answer Accepted 15 Answers 13 Votes
Snail mucous has many advantages, what is the best way to extract it without changing its composition?
land snails like Eremina desertorum, how can i get its mucous without killing or hurting it?
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2 Answers 0 Votes
How does a friccohesity quantum mechanically correlate shear stress and shear rate with surface tension or energy to smoothen systolic and diastolic heart beat with 120/80 mmHg blood pressure?
Pumping large sized food particles with least surface energy, heart needs more energy while for small sized a less. The higher friccohesity predicts small sized food particles with more adherence with blood serum with higher energy moderating shear rate with surface energy.
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Answer Accepted 1 Answer 1 Vote
Can Levodopa and Renin-angiotensin system alter the intercellular tight junction (TJ) proteins in the epithelial cells in colorectal adenocarcinoma cell line (in vitro)?
Colorectal adenocarcinoma cell line (Caco-2) express tight junctions from 17-21 days. Levodopa is the precursor of dopamine, a well-known neurotransmitter, owever it also porduce effect in the gut. The renin-angiotensin system is responsible for maintaining homeostais and regulate blood pressure and volume.
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Answer Accepted 4 Answers 1 Vote
What conference(s) do you find most useful for pharmacovigilance related topics?
Which conference(s) are best for learning, networking and presenting on pharmacovigilance?
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