Pings
-
6 Answers 2 Votes
Role of humanized immune system mice in to study the infectious and systemic inflammatory disease.
Whether the humanized immune system (HIS) mice help developing therapeutic interventions against infectious and inflammatory diseases? Whether HIS mice may revolutionize the translational biomedical research
-
Answer Accepted 10 Answers 6 Votes
No threshold approach in the risk assessment of genotoxic carcinogen. Is it still well supported by current knowledge of carcinogenesis?
No threshold approach is routinely applied in the risk assessment of genotoxic carcinogens. How this approach is supported by data? Isn´ t it somewhat obsolete?
-
6 Answers 2 Votes
When the policy exists to share postprints freely on personal sites, why do researchers often refrain from doing so, and what incentives or constraints drive that hesitation?
There has been extensive discussion about the funding model for research publications. Large publishing houses do not fund research themselves; instead, they charge substantial subscription fees or open-access publishing fees. Keeping articles behind paywalls can impede open science and broad access to knowledge. Nevertheless, many publishers grant authors the right to share postprints of their papers immediately on their non-commercial personal blogs or websites. Despite this permission,...
-
4 Answers 0 Votes
How can medical microrobots improve our awareness regarding the diagnosis and treatment of diseases?
How can medical microrobots improve our awareness regarding the diagnosis and treatment of diseases?
-
Answer Accepted 1 Answer 1 Vote
What are the current hot topics in oncology, and where is the future of cell, immune, and small molecule therapies headed?
Beyond established CAR-T and checkpoint inhibitors, what emerging trends (e.g., protein degraders, AI-driven drug discovery, off-the-shelf cell therapies) are shaping the next decade of cancer treatment? Which modalities show the most promise for solid tumors?
-
2 Answers 0 Votes
Why is the ammonia/ammonium concentration highly increased during storage of human urine?
Hydrolysis of urine Why is the ammonia/ammonium concentration highly increased during storage of human urine?
-
Answer Accepted 1 Answer 0 Votes
What are the current hot topics in the study of critical points during the process of cell mutation and development into tumors? How to conduct in-depth research on the future use of AI?
Tumorigenesis is not a linear accumulation of mutations but rather a dynamic process punctuated by critical transition points—windows during which normal cells cross irreversible thresholds toward dysplasia, carcinoma in situ, and ultimately invasive malignancy. Understanding the molecular and ecological drivers of these “tipping points” is fundamental to early interception and prevention. I would like to ask the cancer biology and computational oncology community: Which specific transition...
-
Answer Accepted 6 Answers 7 Votes
Do recurring evaluations by research funders genuinely enhance research quality and societal impact, or do they merely create unnecessary administrative burdens?
Many research funders require periodic evaluations of projects to ensure accountability, monitor progress, and assess impact. While such evaluations can drive improvements in research design, transparency, and relevance, they can also consume significant time and resources. This raises the question of whether the benefits—such as higher-quality outputs and stronger societal contributions—outweigh the potential drawbacks, including administrative overload and reduced time for actual research.
-
Answer Accepted 1 Answer 0 Votes
Does the anti-aging gene Sirtuin 1 need to be measured in early disease screening in COVID-19 and AIDS patients?
The defective gene in the global chronic disease epidemic has now been linked to the anti-aging gene Sirtuin 1. Sirtuin 1 is now an important gene for consideration in Frontiers and Genetics. Nutritional regulation of Sirtuin 1 is critical to nuclear receptors/transcription factors that are involved with glucose homeostasis, immune system, body temperature regulation, stem cell therapy and mitochondrial biogenesis. Plasma Sirtuin 1 levels may be of critical interest to COVID-19, AIDS and the...
-
3 Answers 1 Vote
How many samples do you need to analyze for effective blood plasma products quality control?
A blood bank is set up with a laboratory for the preparation of blood components. Product quality control (e.g. plasma sterility) should be performed. How many samples do you need to analyze for effective control? How do you calculate this number? Does it vary depending on the total number of components produced?
Pings FAQ
What is a Ping?
A Ping is a single science-based question. The question comes from a fellow SciPinion Expert who is seeking input from the expert community. All participation in this service (i.e. asking or answering questions) is voluntary and anonymous if you prefer.
Can I post a Ping?
Yes, all SciPinion Experts are able to ask questions for the expert community to answer, provided you have Ping Credits. All Experts start with 3 Ping Credits (i.e., can ask 3 questions), and have the opportunity to earn more (e.g., by answering Pings from other experts, applying to panel opportunities).
Can I sponsor a Paid Ping?
Yes, please contact SciPinion if you would like to sponsor a Paid Ping.
What do I get for answering a Ping?
By answering a question from a fellow SciPinion Expert you earn 1 Ping Credit, which allows you to sponsor your own Ping (e.g., for every question you answer, you can ask your own question)
You also receive the satisfaction of helping your fellow experts and supporting the scientific community.