Pings
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0 Answers 0 Votes
What are the most popular directions in tumor immune research that can be linked to traditional Chinese medicine at present?
Traditional Chinese medicine has long been practiced in cancer care, yet its mechanistic interface with modern tumor immunology remains underexplored. Given the recent advances in immuno-oncology—particularly in areas such as gut microbiota modulation, tumor microenvironment reprogramming, metabolic reprogramming of immune cells, and reversal of T cell exhaustion—I am interested in identifying which of these frontiers offer the most scientifically rigorous and translatable entry points for...
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4 Answers 0 Votes
How can medical microrobots improve our awareness regarding the diagnosis and treatment of diseases?
How can medical microrobots improve our awareness regarding the diagnosis and treatment of diseases?
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5 Answers 1 Vote
For a change in the peer-reveiwing as an urgent need?
With an increasing number of Journal and other publication, the review by peer started to be difficult and very often nonqualified reviewers are solicited. Very often now the Journal send us a list that ressemble the directory a. This is a problem since many of the persons listed here do not have even a record over 10 and there are supposed to review works they don't know, and they are not qualified. I would like to start a huge discussion that can be sent to the main Journal to change the...
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9 Answers 13 Votes
Can pesticides penetrate into fruits and vegetables as well as on their surface? Is it possible to completely remove pesticide residue?
Can pesticides penetrate not only the outside but also the inside of vegetables and fruits? How to remove pesticide residue from the surface? Is it possible to completely remove pesticide residue?
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4 Answers 0 Votes
What threshold of urinary cadmium (Cd-U) is currently considered indicative of early renal tubular dysfunction in exposed adult populations?
I am conducting a study on chronic environmental cadmium exposure and its nephrotoxic effects, particularly focusing on early biomarkers of renal tubular damage. Several sources suggest 2 µg/g creatinine as a reference point, but variability exists depending on population, sex, and co-exposure. Could experts clarify which threshold (e.g. 1 µg/g, 2 µg/g, or 5 µg/g creatinine) is most reliable or currently used in risk assessments and clinical practice?
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Answer Accepted 1 Answer 0 Votes
Which method is most effective for conducting a personnel needs analysis for Environmental Health Officers?
This study seeks to determine which method is most effective for conducting a personnel needs analysis among Environmental Health Officers (EHOs). Key research questions include: How effective is the Workload Indicators of Staffing Need (WISN) method in estimating appropriate staffing levels for EHOs? What are the strengths and limitations of using task analysis to understand EHO job roles and responsibilities? To what extent does competency gap analysis help identify training and skill...
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Answer Accepted 1 Answer 0 Votes
Do various CLINICIANS need to monitor Sirtuin 1 gene expression and plasma Sirtuin 1 levels with relevance to various drug therapies in patients?
Specific genes that are involved in anti-aging and epigenetics are sensitive to nutritional regulation, oxidative stress and the development of insulin resistance that can result from changes in cellular chromatin, DNA methylation and histone modifications with relevance to the global chronic disease epidemic. The defective gene in the global chronic disease epidemic has now been linked to the anti-aging gene Sirtuin 1. Nutritional regulation of Sirtuin 1 is critical to nuclear...
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14 Answers 2 Votes
Why is the death rate of male in heart disease always higher than that of women? How can a male achieve that power?
It is clear from the report of WHO that the death rate of Male in heart-disease is higher than that of women. This observation suggests that the woman may have some physical advantage. Besides, differential food, beverage-drinking, and smoking habit, etc. can also contribute to it. For example, the habit of consuming oily foods (saturated fat harms heart) is more in the case of some individuals (taste matter). Although many people are aware of the issue, they can't change the food-habits....
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6 Answers 0 Votes
In an age where the scientific community is often seen as a guarantor and where short-termist policies are the norm, is there still a place for independent research ?
Calls for projects are becoming increasingly time-consuming, with researchers facing intense competition for funding, which is monopolising ancillary services, consultants and even lobbyists. Budgets allocated to research are determined by priorities that vary according to political choices, the coherence of which can legitimately be questioned. All too often, announced policies reflect subjective choices based on unfounded presuppositions, or even deny established scientific facts....
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0 Answers 0 Votes
In what way is fluence-dependent photobiomodulation at 660 nm modulating mitochondrial-driven motility and acrosomal membrane stability in human spermatozoa, and can a simulation-based model incorpora
This question integrates: Biophysical mechanisms (mitochondrial activity, acrosomal membrane) Photobiomodulation parameters (fluence, wavelength) Computational modeling (simulation-based, biological noise) Clinical translation (fertility optimization
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