Pings
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Answer Accepted 1 Answer 1 Vote
What are the current hot topics in oncology, and where is the future of cell, immune, and small molecule therapies headed?
Beyond established CAR-T and checkpoint inhibitors, what emerging trends (e.g., protein degraders, AI-driven drug discovery, off-the-shelf cell therapies) are shaping the next decade of cancer treatment? Which modalities show the most promise for solid tumors?
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3 Answers 0 Votes
How can medical microrobots improve our awareness regarding the diagnosis and treatment of diseases?
How can medical microrobots improve our awareness regarding the diagnosis and treatment of diseases?
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2 Answers 0 Votes
Why is the ammonia/ammonium concentration highly increased during storage of human urine?
Hydrolysis of urine Why is the ammonia/ammonium concentration highly increased during storage of human urine?
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Answer Accepted 1 Answer 0 Votes
What are the current hot topics in the study of critical points during the process of cell mutation and development into tumors? How to conduct in-depth research on the future use of AI?
Tumorigenesis is not a linear accumulation of mutations but rather a dynamic process punctuated by critical transition points—windows during which normal cells cross irreversible thresholds toward dysplasia, carcinoma in situ, and ultimately invasive malignancy. Understanding the molecular and ecological drivers of these “tipping points” is fundamental to early interception and prevention. I would like to ask the cancer biology and computational oncology community: Which specific transition...
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Answer Accepted 7 Answers 5 Votes
No threshold approach in the risk assessment of genotoxic carcinogen. Is it still well supported by current knowledge of carcinogenesis?
No threshold approach is routinely applied in the risk assessment of genotoxic carcinogens. How this approach is supported by data? Isn´ t it somewhat obsolete?
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5 Answers 2 Votes
Role of humanized immune system mice in to study the infectious and systemic inflammatory disease.
Whether the humanized immune system (HIS) mice help developing therapeutic interventions against infectious and inflammatory diseases? Whether HIS mice may revolutionize the translational biomedical research
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5 Answers 1 Vote
For a change in the peer-reveiwing as an urgent need?
With an increasing number of Journal and other publication, the review by peer started to be difficult and very often nonqualified reviewers are solicited. Very often now the Journal send us a list that ressemble the directory a. This is a problem since many of the persons listed here do not have even a record over 10 and there are supposed to review works they don't know, and they are not qualified. I would like to start a huge discussion that can be sent to the main Journal to change the...
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Answer Accepted 19 Answers 5 Votes
Impact of Food Regulation on Chronic Disease
To what extent do you believe strict governmental regulation of food safety and marketing could reduce the incidence of chronic diseases in the population? - Up to 30% - Around 50% - Up to 70% - Minimal effect - It depends on cultural factors
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Answer Accepted 1 Answer 0 Votes
Does the anti-aging gene Sirtuin 1 need to be measured in early disease screening in COVID-19 and AIDS patients?
The defective gene in the global chronic disease epidemic has now been linked to the anti-aging gene Sirtuin 1. Sirtuin 1 is now an important gene for consideration in Frontiers and Genetics. Nutritional regulation of Sirtuin 1 is critical to nuclear receptors/transcription factors that are involved with glucose homeostasis, immune system, body temperature regulation, stem cell therapy and mitochondrial biogenesis. Plasma Sirtuin 1 levels may be of critical interest to COVID-19, AIDS and the...
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14 Answers 2 Votes
Why is the death rate of male in heart disease always higher than that of women? How can a male achieve that power?
It is clear from the report of WHO that the death rate of Male in heart-disease is higher than that of women. This observation suggests that the woman may have some physical advantage. Besides, differential food, beverage-drinking, and smoking habit, etc. can also contribute to it. For example, the habit of consuming oily foods (saturated fat harms heart) is more in the case of some individuals (taste matter). Although many people are aware of the issue, they can't change the food-habits....
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