Pings
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3 Answers 0 Votes
Which impact has Bempedoic Acid on atherosclrosis plaque stability ?
Mechanism of action
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6 Answers 2 Votes
Role of humanized immune system mice in to study the infectious and systemic inflammatory disease.
Whether the humanized immune system (HIS) mice help developing therapeutic interventions against infectious and inflammatory diseases? Whether HIS mice may revolutionize the translational biomedical research
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Answer Accepted 2 Answers 0 Votes
Does Yoghurt, Cheese and Milk consumption reduce gut gram negative bacteria and toxic plasma bacterial lipopolysaccharides?
RELEVANT REFERENCES: 1. Sharma, A and IJ Martins. The role of Microbiota in the pathogenesis of Alzheimer’s disease. Acta Scientific Nutritional Health. 7.7 (2023): 108-118. 2. Bacterial Lipopolysaccharides and Neuron Toxicity in Neurodegenerative Diseases. Neurology Research and Surgery. 2018; 1(1): 1-3. 3. Overnutrition Determines LPS Regulation of Mycotoxin Induced Neurotoxicity in Neurodegenerative Diseases. Int J Mol Sci. 201516(12): 29554–29573.
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Answer Accepted 5 Answers 0 Votes
If you have swab cultures from burn patients, what computational tools will you use to analyze the antimicrobial resistance among those cultures?
I am interested in carbapenem resistance or metallo-beta-lactamases.
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Answer Accepted 2 Answers 0 Votes
Does Yoghurt, Cheese and Milk consumption reduce gut gram negative bacteria and toxic plasma bacterial lipopolysaccharides?
RELEVANT REFERENCES: 1. Sharma, A and IJ Martins. The role of Microbiota in the pathogenesis of Alzheimer’s disease. Acta Scientific Nutritional Health. 7.7 (2023): 108-118. 2. Bacterial Lipopolysaccharides and Neuron Toxicity in Neurodegenerative Diseases. Neurology Research and Surgery. 2018; 1(1): 1-3. 3. Overnutrition Determines LPS Regulation of Mycotoxin Induced Neurotoxicity in Neurodegenerative Diseases. Int J Mol Sci. 201516(12): 29554–29573.
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Answer Accepted 1 Answer 0 Votes
Are surveillance and 'omics' profiling studies being overhyped, and eating up the limited funding for scientific research?
These day, there has been a considerable increase in publications reporting some sort of genomics/transcriptomics/metagenomics profiling. While these 'omics' tools are quite useful, many researchers simply adopt them as they guarantee some 'data' output, irrespective of sample type. Whatever sample you take, it will always have some microbial species, many genes, and you can easily report this 'profiling'. To make your study look 'big', you can increase the sample size. Such studies get...
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Answer Accepted 11 Answers 3 Votes
How far do you feel Cough syrups really help in viral cough usually dry without phlegm?
People specially after Post covid era, consuming 2-3 cough syrup bottles which are easily available over the counter without looking for composition, rationale and benefits. Is it really helpful or harmful?
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18 Answers 8 Votes
Is Oxidative Stress sufficient by itself as an indicator and compelling basis for a carcinogenic concern?
Oxidative Stress as a Precursor and Mechanism for Carcinogenicity IARC and others (Smith et al) have identified 10 key characteristics which may be used/considered in the evaluation of carcinogenicity, one of which is oxidative stress. How strong or compelling, if at all, would the data need to be for considering OS as a putative and defensible MOA for carcinogenicity, or would there need to be other tangential/correlative data (e.g., tumors) available. In other words, is OS sufficient by...
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12 Answers 3 Votes
Any herbal medicines used for hepatitis, possible mechanism of action, and if possible attached pictures of plants with citations
Any herbal medicines used for hepatitis, possible mechanism of action, and if possible attached pictures of plants with citations
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Answer Accepted 8 Answers 0 Votes
What is the relationship between free radicals and the inflammation process during Chronic diseases?
OxInflammation process is a complex and systemic event that occurs after cellular and tissue injury. The knowledge about both processes is that they coexist, but already known that possibly the inflammatory response is responsible for the generation of a pro-oxidative environment due to the production of Free radicals and Reactive Oxygen species (ROS), especially in chronic diseases. In normal tissue occurs the activation of efficient machinery able to control the oxidative stress, however,...
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