Pings
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5 Answers 0 Votes
What deep learning strategies best balance accuracy and interpretability in medical image segmentation for disease progression analysis?
Medical imaging (CT/MRI) segmentation is vital for tracking disease, but black-box models reduce clinical trust. Methods like explainable AI (XAI), uncertainty quantification, and hybrid modeling may bridge this gap. What approaches are most promising?
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1 Answer 0 Votes
Artificial intelligence has brought great hope to advancing our understanding of severe inflammation by simulating complex signal networks and molecular mechanisms that determine disease trajectories.
Artificial intelligence has brought great hope to advancing our understanding of severe inflammation by simulating complex signal networks and molecular mechanisms that determine disease trajectories. The core of this work is pathways such as NF - κ B, MAPK, and JAK-STAT, which regulate the expression of pro-inflammatory cytokines and mediators. These pathways are regulated by post-translational modifications, transcription factor dynamics, and crosstalk with damage associated molecular...
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Answer Accepted 1 Answer 1 Vote
What are the current hot topics in oncology, and where is the future of cell, immune, and small molecule therapies headed?
Beyond established CAR-T and checkpoint inhibitors, what emerging trends (e.g., protein degraders, AI-driven drug discovery, off-the-shelf cell therapies) are shaping the next decade of cancer treatment? Which modalities show the most promise for solid tumors?
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0 Answers 0 Votes
What is the current research progress on the role of the JAK/STAT/mTOR pathway in liver inflammation during liver failure, and is it considered a core pathway in this process?
I am studying the regulatory network of liver inflammation in the pathogenesis of liver failure, especially acute‑on‑chronic liver failure (ACLF). My current focus is on the phosphorylation activation of the JAK/STAT pathway and its downstream mTOR signaling in mediating hepatocyte death, macrophage polarization, and the inflammatory storm. I would like to know the latest research progress on this pathway—for example, whether it involves intercellular crosstalk—and whether the JAK/STAT/mTOR...
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5 Answers 0 Votes
How to examine for power of grip in a patient with weakness?
When we do clinical examination for weakness, power is ascertained by MRC grading. However, for grip, MRC grading cannot be used. Is there any method to examine hand grip power other than using dynamometer
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6 Answers 4 Votes
How might AI-assisted peer review tools reshape scientific publishing, and what safeguards should be implemented to maintain review quality while addressing the increasing volume of submissions?
The peer-reviewing process is being faced with ever-growing challenges as submission rates are still rising exponentially in all areas. Journal editors are faced with the challenge of getting capable reviewers who are ready to volunteer their time, with a result being delays in reviewing, reviewer exhaustion, and worse, compromised quality. Meanwhile, AI technologies are accelerating their ability to review scientific manuscripts for methodology, statistical fitting, plagiarism screenings,...
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Answer Accepted 1 Answer 1 Vote
Assuming your role involves human health, how do you identify those medical practitioners of expertise when you suggest a consultant for your patient?
There is a difference in the skill of physicians to whom we entrust lives. This quotation has relevance to such a dilemma: "What do you call the medical student who graduates first in his class? —-"Doctor" "And what do you call the med student who graduates last in his class? — "Doctor" [Image]
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Answer Accepted 2 Answers 0 Votes
How can AI-enhanced modeling reshape climate-resilient water management in data-scarce regions over the next decade?
Water security is becoming one of the most critical challenges of our time, particularly in regions where hydrological data is scarce or unreliable. At the same time, artificial intelligence and machine learning are revolutionizing how we model environmental systems. The question is: Can these technologies bridge the data gap, improve decision-making, and help design sustainable, climate-resilient water management systems? We're looking for scientific insights, innovative use cases, and...
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Answer Accepted 3 Answers 1 Vote
What’s the most creative way researchers have used big data or AI to strengthen evidence-based medicine in recent years?
For example, are there cases where AI discovered hidden patterns in old clinical trial data, predicted drug interactions before human testing, or identified new risk factors from wearable health devices?
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Answer Accepted 3 Answers 3 Votes
Are the Government Doctors well paid even after having so much workload?
Even after working non-stop the Physicians at Government Institutes and Hospitals are lowly paid.
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