Pings
-
1 Answer 0 Votes
What are the current hot topics in the study of critical points during the process of cell mutation and development into tumors? How to conduct in-depth research on the future use of AI?
Tumorigenesis is not a linear accumulation of mutations but rather a dynamic process punctuated by critical transition points—windows during which normal cells cross irreversible thresholds toward dysplasia, carcinoma in situ, and ultimately invasive malignancy. Understanding the molecular and ecological drivers of these “tipping points” is fundamental to early interception and prevention. I would like to ask the cancer biology and computational oncology community: Which specific transition...
-
0 Answers 0 Votes
Do we need quantum computers to develop treatment plans for tumors using artificial intelligence?
Do we truly need quantum computers to develop AI-driven treatment plans for tumors, or can classical computing—with better algorithms and hardware—still meet the challenge? Artificial intelligence is already being used in radiotherapy planning, drug regimen selection, and multi-omics prediction, but as models grow more complex and begin to integrate real-time imaging, genomic data, and spatiotemporal tumor dynamics, computational demands are rising sharply. Quantum computing is often proposed...
-
0 Answers 0 Votes
Which is the main trigger molecule in the study of inflammatory cytokine storm?
Cytokine storm is a life-threatening hyperinflammatory response observed in infections, autoimmunity, and CAR-T therapy, and while molecules such as IL-6, TNF-α, IFN-γ, and HMGB1 are clearly involved, a fundamental debate remains: is there a single non-redundant master trigger molecule, or is cytokine storm inherently a network-driven phenomenon where multiple pathways activate in parallel and amplify each other through positive feedback loops with no single initiator? If you believe a master...
-
Answer Accepted 7 Answers 2 Votes
No threshold approach in the risk assessment of genotoxic carcinogen. Is it still well supported by current knowledge of carcinogenesis?
No threshold approach is routinely applied in the risk assessment of genotoxic carcinogens. How this approach is supported by data? Isn´ t it somewhat obsolete?
-
6 Answers 2 Votes
Role of humanized immune system mice in to study the infectious and systemic inflammatory disease.
Whether the humanized immune system (HIS) mice help developing therapeutic interventions against infectious and inflammatory diseases? Whether HIS mice may revolutionize the translational biomedical research
-
6 Answers 4 Votes
How might AI-assisted peer review tools reshape scientific publishing, and what safeguards should be implemented to maintain review quality while addressing the increasing volume of submissions?
The peer-reviewing process is being faced with ever-growing challenges as submission rates are still rising exponentially in all areas. Journal editors are faced with the challenge of getting capable reviewers who are ready to volunteer their time, with a result being delays in reviewing, reviewer exhaustion, and worse, compromised quality. Meanwhile, AI technologies are accelerating their ability to review scientific manuscripts for methodology, statistical fitting, plagiarism screenings,...
-
4 Answers 0 Votes
What deep learning strategies best balance accuracy and interpretability in medical image segmentation for disease progression analysis?
Medical imaging (CT/MRI) segmentation is vital for tracking disease, but black-box models reduce clinical trust. Methods like explainable AI (XAI), uncertainty quantification, and hybrid modeling may bridge this gap. What approaches are most promising?
-
15 Answers 1 Vote
How should irrelevant comment(s) from a peer reviewer be handled?
Some times an irrelevant comments is made on a peer review report based on which a paper is rejected and that makes the author very discouraging. Like "Proper discussion is not made why apple is red" while the paper is on lily flower. The answer could be any of the same a) The editorial board should take care of such comments and provide the full support to evaluate the paper a s per merit rather than rejection. b) The paper be rejected and resubmitted to the same or other Journal citing the...
-
1 Answer 0 Votes
How can advances in electrochemical CO₂ conversion improve scalability of carbon-to-fuel technologies while minimizing energy demand and byproduct formation?
As a specialist in CO₂ reduction, my work focuses on advancing pathways that move beyond capture and storage toward scalable, value-added solutions. Current approaches including mineralization, electrochemical conversion, and bio-catalytic processes show potential but face challenges of efficiency, energy demand, and long-term stability. A critical next step is identifying how chemical, mineral, or catalytic enhancements can accelerate these processes while maintaining sustainability and...
-
8 Answers 4 Votes
How do you justify (or would you justify) a new research study to ensure it doesn’t unnecessarily duplicate previous work or repeat past methodological mistakes?
I’m currently working on a PhD thesis focused on Evidence-Based Research (EBR), particularly on how researchers use (or fail to use) prior evidence (similar studies), to justify and design new research. I’d love to hear real-world experiences, whether from preparing research proposals or evaluating them. Do you use any structured or unstructured method to be aware of all relevant prior research? How do you support your judgments (e.g., demonstrating that no prior studies exist, or that...
Pings FAQ
What is a Ping?
A Ping is a single science-based question. The question comes from a fellow SciPinion Expert who is seeking input from the expert community. All participation in this service (i.e. asking or answering questions) is voluntary and anonymous if you prefer.
Can I post a Ping?
Yes, all SciPinion Experts are able to ask questions for the expert community to answer, provided you have Ping Credits. All Experts start with 3 Ping Credits (i.e., can ask 3 questions), and have the opportunity to earn more (e.g., by answering Pings from other experts, applying to panel opportunities).
Can I sponsor a Paid Ping?
Yes, please contact SciPinion if you would like to sponsor a Paid Ping.
What do I get for answering a Ping?
By answering a question from a fellow SciPinion Expert you earn 1 Ping Credit, which allows you to sponsor your own Ping (e.g., for every question you answer, you can ask your own question)
You also receive the satisfaction of helping your fellow experts and supporting the scientific community.