Pings
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Answer Accepted 2 Answers 0 Votes
In developing bioresorbable metallic implants for bone applications, what do you think are the biggest challenges?
Presently, a lot of research is going on based on magnesium, zinc, and iron for being used as temporary implants for orthopedic applications. Despite its advantages, widespread adoption in clinical settings still presents numerous challenges.
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Answer Accepted 5 Answers 0 Votes
If you have swab cultures from burn patients, what computational tools will you use to analyze the antimicrobial resistance among those cultures?
I am interested in carbapenem resistance or metallo-beta-lactamases.
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6 Answers 4 Votes
How might AI-assisted peer review tools reshape scientific publishing, and what safeguards should be implemented to maintain review quality while addressing the increasing volume of submissions?
The peer-reviewing process is being faced with ever-growing challenges as submission rates are still rising exponentially in all areas. Journal editors are faced with the challenge of getting capable reviewers who are ready to volunteer their time, with a result being delays in reviewing, reviewer exhaustion, and worse, compromised quality. Meanwhile, AI technologies are accelerating their ability to review scientific manuscripts for methodology, statistical fitting, plagiarism screenings,...
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Answer Accepted 3 Answers 2 Votes
Does insulin therapy activate the anti-aging gene Sirtuin 1 that is critical for the prevention of insulin iresistance?
The anti-aging gene Sirtuin 1 is important to the prevention of accelerated aging and diabetes. Sirtuin 1 activators are critical to the treatment of diabetes, cardiovascular disease and Alzheimer’s disease. Sirtuin 1 inhibitors cause insulin resistance and reduce plasma Sirtuin 1 levels. Insulin therapy is critical to the treatment of diabetes and plasma Sirtuin 1 levels need to be measured with relevance to the treatment and prevention of insulin resistance. RELEVANT REFERENCES: 1. ...
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3 Answers 0 Votes
What threshold of urinary cadmium (Cd-U) is currently considered indicative of early renal tubular dysfunction in exposed adult populations?
I am conducting a study on chronic environmental cadmium exposure and its nephrotoxic effects, particularly focusing on early biomarkers of renal tubular damage. Several sources suggest 2 µg/g creatinine as a reference point, but variability exists depending on population, sex, and co-exposure. Could experts clarify which threshold (e.g. 1 µg/g, 2 µg/g, or 5 µg/g creatinine) is most reliable or currently used in risk assessments and clinical practice?
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Answer Accepted 7 Answers 2 Votes
Do you think general physicians or medical doctors might be redundant when AGI is fully developed?
This is a burning topic in medical or clinicians' circles globally as it might have the potential to shake up the medical profession due to the concerted efforts by AI enthusiasts by questioning the relevance of the doctors e.g. general physicians if not all (e.g. medial surgeons or specialists). This may be a challenge for the future healthcare planners and might need a thorough debate. The following reference might give a glimpse and assist while answering for my ping question. Kazzazi F....
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Answer Accepted 1 Answer 0 Votes
I am conducting a field experiment using a randomized complete block design. The layout includes 5 blocks, each of equal land area. Within each block, there are 5 plots, and each plot receives a diffe
I am conducting a field experiment using a randomized complete block design. The layout includes 5 blocks, each of equal land area. Within each block, there are 5 plots, and each plot receives a different single treatment. These 5 treatments are repeated across all blocks, so each treatment is replicated five times in total—once per block. My question concerns sample collection for a single treatment. What is the scientifically valid and recommended method for collecting samples and...
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7 Answers 4 Votes
How do you justify (or would you justify) a new research study to ensure it doesn’t unnecessarily duplicate previous work or repeat past methodological mistakes?
I’m currently working on a PhD thesis focused on Evidence-Based Research (EBR), particularly on how researchers use (or fail to use) prior evidence (similar studies), to justify and design new research. I’d love to hear real-world experiences, whether from preparing research proposals or evaluating them. Do you use any structured or unstructured method to be aware of all relevant prior research? How do you support your judgments (e.g., demonstrating that no prior studies exist, or that...
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1 Answer 0 Votes
Which impact has Bempedoic Acid on atherosclrosis plaque stability ?
Mechanism of action
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7 Answers 3 Votes
What is the most important research material in protein bioinformatics? 1. Protein sequence 2. Protein structure 3. Protein-related Software 4. A high-speed computer
A protein's sequence contains its intrinsic properties as a code. Nobel laureate scientist, C. B. Anfinsen proved it through experiments. Unlike sequence, since structures are man-made and obtained under different laboratory conditions, they may contain human error. Further, unlike nucleic acid, to date, the protein-folding code is unknown. So, in my opinion the study of protein sequence is primary. It is better if one can include structure study with it. But little can be said about this...
Pings FAQ
What is a Ping?
A Ping is a single science-based question. The question comes from a fellow SciPinion Expert who is seeking input from the expert community. All participation in this service (i.e. asking or answering questions) is voluntary and anonymous if you prefer.
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You also receive the satisfaction of helping your fellow experts and supporting the scientific community.