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What do you feel are the top science breakthroughs of 2022?

Science magazine recently identified the top science breakthroughs of 2022 - which of these do you feel are the greatest breakthroughs of the past year?

Science magazine recently identified the top science breakthroughs of 2022: https://www.science.org/content/article/breakthrough-2022
Which of these do you feel are the greatest breakthroughs of the past year (please select up to three)