U.S. Federal Approach to Cannabinoid Regulation

This SciPoll wants to understand the scientific opinion from the world’s experts on the U.S. federal approach to cannabinoid regulation including those with and without intoxicating effects.

Cannabis or marijuana (cannabis containing >0.3% delta-9 THC) is currently federally illegal although numerous states have legalized it for adult or medical use. Delta-9 THC is the major intoxicating cannabinoid naturally found in cannabis. In 2018, the Farm Bill legalized hemp (cannabis containing < 0.3% delta-9 THC) which has led to the development of a market with products containing hemp-derived and semi-synthetic cannabinoids made from CBD intended for oral ingestion, topical application, or inhalation (e.g., vaping, smoking) primarily available in states where cannabis (marijuana) has not been legalized at the state-level. These products include CBD and semi-synthetic, intoxicating cannabinoids such as delta-8 THC (an isomer of delta-9 THC), delta-10 THC, THC-OAcetate, THC-P, THC-X, THCjd, HHC, etc. They do not include synthetic cannabinoids like Spice or K2 which act on cannabinoid receptors, but are not derived or synthesized from cannabis or hemp.