Please rate your level of expertise in the following topic areas (1=lowest, 10=highest)

Answer Explanations

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  Expert 2

  Topic Area	1	2	3	4	5	6	7	8	9	10
  PFAS Chemistry	0	0	0	0	0	0	0	0	1	0
  PFAS Toxicology	0	0	0	0	1	0	0	0	0	0
  Mixtures Risk Assessments	0	0	0	0	0	0	1	0	0	0
  Toxicokinetics	0	0	0	0	0	0	1	0	0	0

  My expertise is mainly in the area of analytical chemistry of PFAS, especially measurement in environmental and biological specimens. Over the past 20 years, I have read lot of chemistry papers related to PFAS and some toxicology and exposure/risk assessment papers.

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  Expert 4

  Topic Area	1	2	3	4	5	6	7	8	9	10
  PFAS Chemistry	0	0	0	0	0	0	1	0	0	0
  PFAS Toxicology	0	0	0	0	0	0	0	1	0	0
  Mixtures Risk Assessments	0	0	0	0	0	0	0	1	0	0
  Toxicokinetics	0	0	0	0	0	0	1	0	0	0

  I have been involved in the development of risk management plans related to PFAS in groundwater and drinking water, as well as providing advice to clients concerning the derivation of various jurisdictions' drinking water guidelines and standards for PFAS.

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  Expert 1

  Topic Area	1	2	3	4	5	6	7	8	9	10
  PFAS Chemistry	0	0	1	0	0	0	0	0	0	0
  PFAS Toxicology	0	0	0	0	0	0	0	1	0	0
  Mixtures Risk Assessments	0	0	0	0	1	0	0	0	0	0
  Toxicokinetics	0	0	0	0	0	0	0	0	1	0

  I have worked on toxicokinetic models of PFAS, and reviewed multiple guidance documents reporting results from in vivo and in vitro studies.

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  Expert 3

  Topic Area	1	2	3	4	5	6	7	8	9	10
  PFAS Chemistry	0	0	0	1	0	0	0	0	0	0
  PFAS Toxicology	0	0	0	0	1	0	0	0	0	0
  Mixtures Risk Assessments	0	0	0	0	0	0	0	0	1	0
  Toxicokinetics	0	0	0	0	1	0	0	0	0	0

  I have reviewed articles dealing with PFAS. I am an author on numerous publications on risk assessment methods, science policy, assessment of environmental contaminants, mode of action and adverse outcome pathway, utility of long term and other bioassays, and mixtures risk assessment. In addition to publications in the peer-reviewed press, I have been an author on guidance documents used by authoritative bodies.

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  Expert 7

  Topic Area	1	2	3	4	5	6	7	8	9	10
  PFAS Chemistry	0	0	0	0	0	0	0	0	0	1
  PFAS Toxicology	0	0	0	0	0	1	0	0	0	0
  Mixtures Risk Assessments	0	0	0	0	0	0	0	1	0	0
  Toxicokinetics	0	1	0	0	0	0	0	0	0	0

  I ranked the first three high to highest. Especially as to chemistry and nomenclature, cleaning of nomenclature is necessary, proof of evidence of data, I would like to add some more papers as to the analytical apporaches (what is contained, what is achieved, where applicable).
  PFAS toxicology: I am not an expert in specific endpoints, mechansism, diseases but well aware of the gaps and the interpretation of toxocilogical results and the linkages to the analytical proof for the chemicals. Chemists and toxicologist may have the problem to not differentaite between correlation and causation.
  Mixture assesment: I do not mean the individual approaches but from the dioxin TEF approach know very well the essentials and how many reserachers and agencies redefine or extrapolate by neglecting the basis.
  I thik that toxicokinetics is important but not decisive; not he major criterion for my expertise

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  Expert 9

  Topic Area	1	2	3	4	5	6	7	8	9	10
  PFAS Chemistry	0	0	0	0	0	1	0	0	0	0
  PFAS Toxicology	0	0	0	0	0	0	0	0	1	0
  Mixtures Risk Assessments	0	0	0	0	0	0	1	0	0	0
  Toxicokinetics	0	0	0	0	0	1	0	0	0	0

  I study the immunotoxicity, and to an extent the general toxicity, of PFAS in the laboratory. I understand their basic chemistry, have conducted mixtures studies and participated in mixtures hazard assessments, and have conducted toxicokinetic studies of other compounds.

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  Expert 10

  Topic Area	1	2	3	4	5	6	7	8	9	10
  PFAS Chemistry	0	0	0	0	0	0	0	0	0	1
  PFAS Toxicology	0	0	0	1	0	0	0	0	0	0
  Mixtures Risk Assessments	0	0	0	0	1	0	0	0	0	0
  Toxicokinetics	0	0	0	0	0	0	1	0	0	0

  I'm an environmental organic chemistry primarily but have done quite some research on human exposure and phamarcokinetic modelling. I am well known as an expert on the environmental chemistry of PFAS. I have read a lot of material and been lectured on mixture risk assessment, but would not consider myself an expert on the topic.

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  Expert 6

  Topic Area	1	2	3	4	5	6	7	8	9	10
  PFAS Chemistry	1	0	0	0	0	0	0	0	0	0
  PFAS Toxicology	0	0	0	0	0	0	0	0	0	1
  Mixtures Risk Assessments	0	0	0	0	0	1	0	0	0	0
  Toxicokinetics	0	0	0	0	0	0	0	1	0	0

  My primary expertise is in toxicological analysis for regulatory purposes; for PFAS this includes knowledge of both experimental animal studies; epidemiological studies, development of regulatory standards based on risk assessment and, to some extent, risk assessment approaches for mixtures; Relevant experience includes assistance with the development of Australian health risk assessment methodologies (the seminal enHealth Guidance document 2012) and health-based PFAS guidance values. Is there a process whereby Panel members can provide additional reference material that could assist the project? I have identified a dozen papers additional to those provided that might be helpful.