Why do cancer treatment options (chemotherapies + radiations) have outcome failure rates of 90% (+/-5) for solid tumors?
Despite seven decades of basic science, epidemiological and animal studies or clinical trials on cancer research and therapy, why cancer treatment options (chemotherapies + radiations) have outcome failure rates of 90% (+/-5) for solid tumors, according to governmental and private organizations. Please select your answer among the followings:
1. Need more research funding for epidemiological studies and experimental models of tumors and clinical trials.
2. Cancer is too many (100, 200 or 1000) diseases according to reports by NCI and scientific publications.
3. Cancer immunobiology is very complicated.
4. Lack of sufficient identification of genetic mutations that are present in site-specific cancer microenvironments to develop more effective therapy.
5. Lack of direct evidence between stimuli- (immune triggers)-induced time-course kinetics of immune response alterations toward multistep carcinogenesis.
6. Need effective targeted therapy, precision or personalized medicine and immunotherapy.
7. I can’t answer that.
Please explain your answer.
Drug Discovery Mechanisms of action Medicine Oncology