What is the most important research material in protein bioinformatics? 1. Protein sequence 2. Protein structure 3. Protein-related Software 4. A high-speed computer
A protein's sequence contains its intrinsic properties as a code. Nobel laureate scientist, C. B. Anfinsen proved it through experiments. Unlike sequence, since structures are man-made and obtained under different laboratory conditions, they may contain human error. Further, unlike nucleic acid, to date, the protein-folding code is unknown. So, in my opinion the study of protein sequence is primary. It is better if one can include structure study with it. But little can be said about this code just from the structure.