Is the role of ceramides in neurodegenerative diseases?

 Ceramides, a class of lipid molecules, have been implicated in the pathogenesis of neurodegenerative diseases. Elevated levels of ceramides have been associated with cellular stress, inflammation, and apoptosis, which are processes involved in neurodegeneration. Researchers are investigating the specific mechanisms through which ceramides contribute to diseases like Alzheimer's and Parkinson's, aiming to understand their role and potential therapeutic interventions targeting ceramide pathways. 
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Oleksii Korzh
While ceramides play crucial roles in normal cellular processes, dysregulation of ceramide metabolism has been implicated in the pathogenesis of neurodegenerative diseases. Ceramides can activate inflammatory pathways, leading to the production of pro-inflammatory cytokines and promote apoptosis in neuronal cells.

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