As an editor for peer-reviewed journal, what would you consider appropriate in making a decision to accept a peer-reviewer's report?

When evaluating a peer-reviewed study on surface water resources used for a commercial water operation, it is expected that the reviewer will thoroughly assess the methodology, including water sampling procedures and data analysis. In addition, the reviewer should identify potential oversights and suggest necessary improvements or alternative methods. However, when an expert reviewer raises concerns, and the authors respond with contrary submissions supported by well-detailed references, how would you, as an editor or associate editor, approach this situation?

Would you solely rely on the expert panel's judgment (in this case only one reviewer is holding on maybe out of four), or would you take additional steps to independently verify some of the information provided by the reviewer? Specifically, if the reviewer’s claims are not well-supported by references, would you investigate whether their arguments are sound and scientifically valid, or would you place full trust in their expertise? Given that reviewers may sometimes make claims without proper citations, would you assess the reviewer’s overall credibility, and how would you balance the reviewers' recommendations with the authors' justifications and supporting evidence?

In this question I intend to explore whether, as an editor, you would take steps to independently assess the validity of the peer reviewer’s feedback in situations where the authors challenge the reviewer’s claims with well-supported arguments and references. Would you verify the reviewer’s arguments independently, or would you rely entirely on the reviewer’s expertise, even if their claims are not fully referenced? It's one of the problems I see with some journal peer-reviews these days, where associate editors without the benefit of expert reviewer panels, are felt without a choice to reject manuscripts because they themselves are either not experts or confident enough to reject reviewer claims, that sentimental and not really based on facts.

Accepted
1
Andrew F.
In the case that you cited, I would easily side with the authors. In the case of the holdout reviewer who provided no references and cast aspersions at the manuscript, I would be sure to never use that reviewer again.

It is the reviewer's job to not merely be a subject matter expert, but they must also be current with the literature and substantiate their claims. If the literature conflicts, the support for publication of the manuscript only grows.

As a reviewer and an author, I have seen too many lazily written reviews by other supposed experts who simply wrote "The manuscript is of poor quality" while providing no explanation nor justification. They should be ashamed of themselves.
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Ian James Martins
The reviewer must comment on the abstract and the problem investigated. The reviewer should assess the introduction if it summarizes the relevant research and accurately and clearly states the problem investigated. The reviewer must check if the experimental design is suitable for answering the research question and the authors clearly identify the procedures used, experimental design and hypotheses tested. The reviewer should check if the  manuscript is clearly laid out with relevance to the introduction, methodology, results and conclusion sections. The reviewer should assess if the research builds on previous research and does reference the research work properly. The reviewer must always check for plagiarism before the editor can make a decision on the peer-reveiwer’s report. 

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