How long does it take for a glycoprotein to be synthesised de novo, processed in the ER/Golgi apparatus and transported to the cell membrane?
The trafficking time probably depends on the specific protein, but a ballpark average time is what I'm after.
Please include references or examples.
Please include references or examples.
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7 Answers
Hadi parsian
It is difficult to say the exact time, because it is completely depend to the nature of protein, its size, the glycosylation power and so on, but generally it may takes several minutes to severl hours.
MaxFriesen
It's highly dependent on the specific protein, but as a ballpark it is on the order of a few hours.
There is nothing specific about glycosylation, as compared to other semi-permanent post-translational protein modifications, in terms of timeline for synthesis, modification and transport.
There is nothing specific about glycosylation, as compared to other semi-permanent post-translational protein modifications, in terms of timeline for synthesis, modification and transport.
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Kurt E. Johnson
Kurt E. Johnson, PhD