It seems Duffy negativity does not offer a 100% resistance to vivax malaria in Africans; any clues as to why this is so?????
Duffy polymorphism and malaria, any link?
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3 Answers
Manayesh Bantie
For many years it was believed that Duffy antigen negativity gave complete protection against p.vivax.
However, in studies conducted mainly in east Africa have detected p.vivax in Duffy negative individuals indicating that the parasite may be evolving alternative invasive pathways
However, in studies conducted mainly in east Africa have detected p.vivax in Duffy negative individuals indicating that the parasite may be evolving alternative invasive pathways
Zeinab R. Hassan