Pings
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1 Answer 0 Votes
During animal euthanization at the experiment's end. Did we use the anesthetic dose or an overdose?
They are confused about using anesthesia doses during euthanization. Many researchers use overdose without detecting the dose accurately.
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2 Answers 0 Votes
Should Impact Factor be the standard for judging how sound a journal is?
Impact Factor is about citations and not necessarily quality
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3 Answers 1 Vote
What is the most important part of a scientific article? Let's approach this seriously! Part 2
I have read all the responses to my question, and I find that, except for one, they are largely absurd. There is talk of methodology and results, but as the famous saying goes, “There are lies, big lies, and statistics.” Many articles submitted for publication manipulate data that is either highly misleading or not original at all. I’m unsure if this will be approved on Scipion. What is the most important part of a scientific article? Let’s approach this seriously! I am not at all surprised...
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Answer Accepted 24 Answers 39 Votes
Editors at many reputable journals are having a difficult time finding peers to conduct peer reviews of submitted manuscripts for free. Do you think peer reviewers should get paid for their efforts?
Paid versus non-paid peer reviewing of scientific manuscripts Incentivizing the peer review process
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Answer Accepted 6 Answers 5 Votes
How publication retractions should be handled?
With an alarming rise in number of retracted papers, what the scientific community thinks is the best way to handle them? 1. Should be ignored, giving benefit-of-doubt to the authors 2. Authors with multiple retracted papers should be demoted 3. Organizations with high retraction rates should be banned from entering various rankings, and debar them from government funding for 1-2 years 4. Court trials against the faulty researchers for criminal wastage of public money
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Answer Accepted 2 Answers 1 Vote
Can phytoestrogens slow down aging in women?
Phytoestrogens are a variety of nonsteroidal compounds of plants which are similar to estradiol. They have both anti-estrogenic and estrogen-like effects. It is known that phytoestrogens normalize the condition of the body of women with menopausal syndrome. However, can they compensate for estrogen deficiency and reduce the rate of aging?
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4 Answers 3 Votes
How do you justify (or would you justify) a new research study to ensure it doesn’t unnecessarily duplicate previous work or repeat past methodological mistakes?
I’m currently working on a PhD thesis focused on Evidence-Based Research (EBR), particularly on how researchers use (or fail to use) prior evidence (similar studies), to justify and design new research. I’d love to hear real-world experiences, whether from preparing research proposals or evaluating them. Do you use any structured or unstructured method to be aware of all relevant prior research? How do you support your judgments (e.g., demonstrating that no prior studies exist, or that...
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1 Answer 0 Votes
Why do in vitro studies often show ideal results for new techniques, while clinical outcome studies show no significant difference compared to conventional treatments?
In Endodontics specifically: 1. Irrigation techniques (e.g., GentleWave, PUI): • In vitro: Often show superior bacterial reduction compared to conventional syringe irrigation. • Outcome studies: Many show no statistically significant difference in long-term healing or success rates (e.g., JOE 2022, 2024 papers). • 2. Root canal sealers (e.g., bioceramics vs epoxy): • In vitro: Bioceramic sealers demonstrate better properties (e.g., antimicrobial, biocompatibility). • Outcome studies: No...
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4 Answers 3 Votes
How might AI-assisted peer review tools reshape scientific publishing, and what safeguards should be implemented to maintain review quality while addressing the increasing volume of submissions?
The peer-reviewing process is being faced with ever-growing challenges as submission rates are still rising exponentially in all areas. Journal editors are faced with the challenge of getting capable reviewers who are ready to volunteer their time, with a result being delays in reviewing, reviewer exhaustion, and worse, compromised quality. Meanwhile, AI technologies are accelerating their ability to review scientific manuscripts for methodology, statistical fitting, plagiarism screenings,...
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Answer Accepted 1 Answer 0 Votes
Does insulin therapy activate the anti-aging gene Sirtuin 1 that is critical for the prevention of insulin iresistance?
The anti-aging gene Sirtuin 1 is important to the prevention of accelerated aging and diabetes. Sirtuin 1 activators are critical to the treatment of diabetes, cardiovascular disease and Alzheimer’s disease. Sirtuin 1 inhibitors cause insulin resistance and reduce plasma Sirtuin 1 levels. Insulin therapy is critical to the treatment of diabetes and plasma Sirtuin 1 levels need to be measured with relevance to the treatment and prevention of insulin resistance. RELEVANT REFERENCES: 1. ...
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