Pings
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18 Answers 8 Votes
Is Oxidative Stress sufficient by itself as an indicator and compelling basis for a carcinogenic concern?
Oxidative Stress as a Precursor and Mechanism for Carcinogenicity IARC and others (Smith et al) have identified 10 key characteristics which may be used/considered in the evaluation of carcinogenicity, one of which is oxidative stress. How strong or compelling, if at all, would the data need to be for considering OS as a putative and defensible MOA for carcinogenicity, or would there need to be other tangential/correlative data (e.g., tumors) available. In other words, is OS sufficient by...
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3 Answers 1 Vote
Is important researching the relation between obesogenicity with the space of the cities? How reasons do you give to assess this issue?
Several authors, such as Downs et al. (2020), Mendes et al. (2022); Recine et al.(2022), and Story et al. (2008) address obesity as part of the pandemic frameworks that make up the global obesity/malnutrition syndemic, aggravated by climate change caused by anthropogenic causes. This framework is structured to characterize, then, biological, social and economic interactions of the population, directing to different comorbidities frameworks. Those authors, however, point out that the concept...
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3 Answers 0 Votes
What are the best ways to handle Hawthorne and John Henry effects in a randomized control trials?
What are the best ways to handle Hawthorne and John Henry effects in a randomized control trial where agricultural extension messages are applied to increase consumption of organic vegetables in rural Nigeria
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