Should LOQs and LODs be reported for each analyte?

Answer Explanations

• Yes (please explain)

  Expert 3
  The Loqs may very depending on the analyte. 
• Yes (please explain)

  Expert 9
  Where possible, this should be done. 
• Yes (please explain)

  Expert 2
  Yes, both the LOQs and LODs should generally be reported for each analyte especially in scientific contexts such as pharmaceutical industry, environmental studies, clinical studies and food safety. Reporting the LOQs and LODs is essential for ensuring the analytical accuracy and credibility of the study. This is due to the fact, that different analytes exhibit distinct responses in different instruments like mass spectrometers or chromatographs. Additionally, LOQs and LODs  are required to be reported by  FDA, EPA, EMA, and ISO  in method validation to ensure compliance and scientific rigor. Furthermore, reporting these will help enhance the  transparency and reproducibility of the study, allowing others to assess whether the method is suitable for each target compound. 
• Yes (please explain)

  Expert 4
  In principle: yes - again assuming that the purpose of the study is to report concentrations of MNP present in a sample. It is also needed to not only report the LOQ of the analytical fluid used (digest or extract) but it should also be added how this translates into the LOQ in actual samples of a specific weight.
• Yes (please explain)

  Expert 5
  For Py-GC/MS, each analyte has a different response factor, therefore the LOQ/LOD for each analyte will not be the same.
• Yes (please explain)

  Expert 6
  As each analyte should have different response factor on the selected technique and on different techniques. Thus, LOQs and LODs should reported for each analyte unless the technique has a universal detection mechanism. Then one set of LOQ/LOD is ok. But current there is no such technique to my knowledge. 
• Yes (please explain)

  Expert 8
  Yes, especially for py-GCMS. I would go even farther that each sample can have a different LOD based on the quantity that was extracted. 
• Yes (please explain)

  Expert 7
  This is the best practice to provide reliable results, and should be provided if time and funding allow. 
• Yes (please explain)

  Expert 1
  While LOD/LOQ for each MNP type is not critical when spectroscopy/microscopy methods are used, reporting of LOD/LOQ for each MNP type is important for methods using pyrolysis GCMS.  It is because sensitivity of MS towards each type of MNP is different.  Pyrolysis GCMS measures mass of MNP not the number of MNP.