Any herbal medicines used for hepatitis, possible mechanism of action, and if possible attached pictures of plants with citations
Any herbal medicines used for hepatitis, possible mechanism of action, and if possible attached pictures of plants with citations
Biochemistry
Cell biology
Drug Discovery
Food Safety
Hepatic toxicology
Hadi parsian
There are a lot of herbal medicine for this purpose:
doi: 10.2147/HMER.S402975
DOI: https://doi.org/10.22246/jikm.2021.42.4.455
DOI:10.1089/act.2010.16308
doi: 10.2147/HMER.S402975
DOI: https://doi.org/10.22246/jikm.2021.42.4.455
DOI:10.1089/act.2010.16308
Rolf Teschke
Question of herbal medicines treating hepatitis is not specific enough as there are many types of hepatitis that may require different medicinal herbs. In gerenal, RCTs espeially from studies in Asia including China with its TCMs are often of poor quality. In addition, many herbal mediccines may be hepatotoxic. References:
Trans Gastroenterol Hepatol 2021; 6: 51; Medicines 2020;7: 62.
Trans Gastroenterol Hepatol 2021; 6: 51; Medicines 2020;7: 62.
Nikola Stojanovic
In Serbia, Lycopodium clavatum tea is used for treatment of damaged liver. Some research is done on this topic:
https://www.sciencedirect.com/science/article/abs/pii/S1475491614000721
https://www.sciencedirect.com/science/article/abs/pii/S1475491614000721
RS
Ganesh, S.; Joshi, N.; Jain, M.K.; Sharma, L.; Desai, A.; Rafiq, M.; Babu, U.V.; Kumawat, R. Clinical and Safety Evaluation of Liv.52 in Alcoholic Liver Disease: A Review. Gastroenterol. Insights 2022, 13, 377-386. https://doi.org/10.3390/gastroent13040037
Gabriel
Silymarin (medicinal plant Silybum marianum (L.) Gaertn)
doi: 10.1007/s12325-020-01251-y. Epub 2020 Feb 17.
doi: 10.1007/s12325-020-01251-y. Epub 2020 Feb 17.
Sriram
There are numerous articles of anti-hepatitic property of plant extracts. Are you looking for in-vitro activities or in vivo activities.
Manzer H. Siddiqui, Saud A. Alamri, Mohamed H. Al-Whaibi, Zahid Hussain, Hayssam M. Ali & Mohamed E. El-Zaidy (2017) A mini-review of anti-hepatitis B virus activity of medicinal plants, Biotechnology & Biotechnological Equipment, 31:1, 9-15, DOI: 10.1080/13102818.2016.1240593
Arbab AH, Parvez MK, Al-Dosari MS, Al-Rehaily AJ. In vitro evaluation of novel antiviral activities of 60 medicinal plants extracts against hepatitis B virus. Exp Ther Med. 2017 Jul;14(1):626-634. doi: 10.3892/etm.2017.4530. Epub 2017 May 31. PMID: 28672977; PMCID: PMC5488430.
Manzer H. Siddiqui, Saud A. Alamri, Mohamed H. Al-Whaibi, Zahid Hussain, Hayssam M. Ali & Mohamed E. El-Zaidy (2017) A mini-review of anti-hepatitis B virus activity of medicinal plants, Biotechnology & Biotechnological Equipment, 31:1, 9-15, DOI: 10.1080/13102818.2016.1240593
Arbab AH, Parvez MK, Al-Dosari MS, Al-Rehaily AJ. In vitro evaluation of novel antiviral activities of 60 medicinal plants extracts against hepatitis B virus. Exp Ther Med. 2017 Jul;14(1):626-634. doi: 10.3892/etm.2017.4530. Epub 2017 May 31. PMID: 28672977; PMCID: PMC5488430.
Mohammed Hawash
this is the recent publications regarding anti-hepatitis herbals
Luo, M., et al., Inhibitory activities of Ranunculus japonicus Thunb. ethanol extract against hepatitis B virus. Journal of Medical Virology, 2022. 94(6): p. 2727-2735.
Luo, M., et al., Inhibitory activities of Ranunculus japonicus Thunb. ethanol extract against hepatitis B virus. Journal of Medical Virology, 2022. 94(6): p. 2727-2735.
2. Jose-Abrego, A., et al., Anti-hepatitis B virus activity of food nutrients and potential mechanisms of action. Annals of Hepatology, 2022: p. 100766.
3. Chen, Z., et al., Antiviral activities of Polygonum perfoliatum L. extract and related phenolic acid constituents against hepatitis B virus. Journal of Medical Virology, 2022. 94(12): p. 5987-5999.
4. Mothana, R.A., et al., Isolation and Characterization of Two Chalcone Derivatives with Anti-Hepatitis B Virus Activity from the Endemic Socotraen Dracaena cinnabari (Dragon’s Blood Tree). Molecules, 2022. 27(3): p. 952.
5. Parvez, M.K., et al., The anti-hepatitis B virus and anti-hepatotoxic efficacies of solanopubamine, a rare alkaloid from Solanum schimperianum. Saudi Pharmaceutical Journal, 2022. 30(4): p. 359-368.
Dr Hossen
1. Hossen MJ, Kim M-Y and Cho JY (2016) MAPK/AP-1-targeted anti-inflammatory activities of Xanthium strumarium. The American journal of Chinese medicine 44:1111-1125.
2. Hossen MJ, Kim M-Y, Kim J-H and Cho JY (2015) AP-1-targeted inhibition of macrophage function and lipopolysaccharide/D-galactosamine-induced hepatitis by Phyllanthus acidus methanolic extract. The American journal of Chinese medicine 43:1137-1158.
3. Hossen MJ, Kim SC, Son Y-J, Baek K-S, Kim E, Yang WS, Jeong D, Park JG, Kim HG and Chung W-J (2015) AP-1-targeting anti-inflammatory activity of the methanolic extract of Persicaria chinensis. Evidence-Based Complementary and Alternative Medicine 2015.
Prasad Variyar
P. R. Raval and R. M. Raval, Treatment of infective hepatitis: Where biomedicine has no answers, Ayurveda has! Anc Sci Life. 2016 Jan-Mar; 35(3): 176–179. doi: 10.4103/0257-7941.179861
U. Latief and R. Ahmad, Herbal remedies for liver fibrosis: A review on the mode of action of fifty herbs. J Tradit Complement Med. 2018 Jul; 8(3): 352–360. doi: 10.1016/j.jtcme.2017.07.002
U. Latief and R. Ahmad, Herbal remedies for liver fibrosis: A review on the mode of action of fifty herbs. J Tradit Complement Med. 2018 Jul; 8(3): 352–360. doi: 10.1016/j.jtcme.2017.07.002
Vinita Vish
Ali M, Khan T, Fatima K, Ali QUA, Ovais M, Khalil AT, Ullah I, Raza A, Shinwari ZK, Idrees M. Selected hepatoprotective herbal medicines: Evidence from ethnomedicinal applications, animal models, and possible mechanism of actions. Phytother Res. 2018 Feb;32(2):199-215. doi: 10.1002/ptr.5957. Epub 2017 Oct 19. PMID: 29047177; PMCID: PMC7167792.
Howida S. Abou Seif, Physiological changes due to hepatotoxicity and the protective role of some medicinal plants, Beni-Suef University Journal of Basic and Applied Sciences, Volume 5, Issue 2,
Howida S. Abou Seif, Physiological changes due to hepatotoxicity and the protective role of some medicinal plants, Beni-Suef University Journal of Basic and Applied Sciences, Volume 5, Issue 2,
2016, Pages 134-146, ISSN 2314-8535, https://doi.org/10.1016/j.bjbas.2016.03.004.
Dr. AN
Yes, there are several medicinal herbs that have been studied to treat the hepatitis virus.
Below are journal papers that you might like to read.
Eric Yarnell and Kathy Abascal.Herbal Medicine for Viral Hepatitis.Alternative and Complementary Therapies.Jun 2010.151-157.http://doi.org/10.1089/act.2010.16308
Nsibirwa, S., Anguzu, G., Kamukama, S. et al. Herbal medicine use among patients with viral and non-viral Hepatitis in Uganda: prevalence, patterns and related factors. BMC Complement Med Ther 20, 169 (2020). https://doi.org/10.1186/s12906-020-02959-8
Rahman Md. Arifur, Ueda Keiji, Honda Tomoyuki. A Traditional Chinese Medicine, Maoto, Suppresses Hepatitis B Virus Production. Frontiers in Cellular and Infection Microbiology, 2021, 10. https://doi.org/10.3389/fcimb.2020.581345
Below are journal papers that you might like to read.
Eric Yarnell and Kathy Abascal.Herbal Medicine for Viral Hepatitis.Alternative and Complementary Therapies.Jun 2010.151-157.http://doi.org/10.1089/act.2010.16308
Nsibirwa, S., Anguzu, G., Kamukama, S. et al. Herbal medicine use among patients with viral and non-viral Hepatitis in Uganda: prevalence, patterns and related factors. BMC Complement Med Ther 20, 169 (2020). https://doi.org/10.1186/s12906-020-02959-8
Rahman Md. Arifur, Ueda Keiji, Honda Tomoyuki. A Traditional Chinese Medicine, Maoto, Suppresses Hepatitis B Virus Production. Frontiers in Cellular and Infection Microbiology, 2021, 10. https://doi.org/10.3389/fcimb.2020.581345
Marilyn Barrett PhD
From NatMed database (https://naturalmedicines-therapeuticresearch-com.eu1.proxy.openathens.net/databases/food,-herbs-supplements/professional.aspx?productid=138) : In people with hepatitis due to a variety of causes, taking a milk thistle extract containing 70% to 80% silymarin (Legalon, Madaus GmbH) 140 mg orally three times daily for 4 weeks reduces symptoms such as jaundice, dark urine, and scleral icterus, but does not improve liver function tests (LFTs) (63210,63317). However, some improvements in LFTs are seen with a silybin-phosphatidylcholine complex (Silipide, Inverni della Beffa Research and Development Laboratories) taken as 160-360 mg orally daily for 2 weeks to 3 months (63320,63321). However, there are methodological problems with these latter studies.
(63210) El-Kamary, S. S., Shardell, M. D., Abdel-Hamid, M., Ismail, S., El-Ateek, M., Metwally, M., Mikhail, N., Hashem, M., Mousa, A., Aboul-Fotouh, A., El-Kassas, M., Esmat, G., and Strickland, G. T. A randomized controlled trial to assess the safety and efficacy of silymarin on symptoms, signs and biomarkers of acute hepatitis. Phytomedicine. 2009;16(5):391-400. View abstract.
(63217) Hawke, R. L., Schrieber, S. J., Soule, T. A., Wen, Z., Smith, P. C., Reddy, K. R., Wahed, A. S., Belle, S. H., Afdhal, N. H., Navarro, V. J., Berman, J., Liu, Q. Y., Doo, E., and Fried, M. W. Silymarin ascending multiple oral dosing phase I study in noncirrhotic patients with chronic hepatitis C. J.Clin.Pharmacol. 2010;50(4):434-449. View abstract.
(63317) Cavalieri S. A controlled clinical trial of Legalon in 40 patients. Gazz Med Ital 1974;133:628-635.
There are many more studies that can be accessed via PubMed. Contact me if you want pdfs of papers.