Pings
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10 Answers 2 Votes
Should Impact Factor be the standard for judging how sound a journal is?
Impact Factor is about citations and not necessarily quality
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7 Answers 0 Votes
Struvite precipitation - What conditions must be satisfied to favor phosphate precipitation by Mg2+ than Ca2+ provided that both ions are present in a solution?
What conditions must be satisfied to favor phosphate precipitation by Mg2+ than Ca2+ provided that both ions are present in a solution?
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5 Answers 0 Votes
Which impact has Bempedoic Acid on atherosclrosis plaque stability ?
Mechanism of action
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8 Answers 1 Vote
What deep learning strategies best balance accuracy and interpretability in medical image segmentation for disease progression analysis?
Medical imaging (CT/MRI) segmentation is vital for tracking disease, but black-box models reduce clinical trust. Methods like explainable AI (XAI), uncertainty quantification, and hybrid modeling may bridge this gap. What approaches are most promising?
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7 Answers 0 Votes
In austere/conflict settings, when does a complex surgery become ethically unjustifiable due to a lack of postoperative resources for managing complications?
As surgeons, we are trained to operate to solve a clinical problem. However, in severely resource-limited or conflict environments, this principle is constantly tested. Consider a scenario: A surgeon has the technical skill to perform a complex procedure (e.g., a pancreaticoduodenectomy for a tumor, or a complex limb salvage after trauma). However, the hospital lacks a reliable ICU, has inconsistent access to blood products, cannot provide parenteral nutrition, and has limited options for...
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3 Answers 0 Votes
Is the role of ceramides in neurodegenerative diseases?
Ceramides, a class of lipid molecules, have been implicated in the pathogenesis of neurodegenerative diseases. Elevated levels of ceramides have been associated with cellular stress, inflammation, and apoptosis, which are processes involved in neurodegeneration. Researchers are investigating the specific mechanisms through which ceramides contribute to diseases like Alzheimer's and Parkinson's, aiming to understand their role and potential therapeutic interventions targeting ceramide pathways.
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2 Answers 0 Votes
What is the most potential drug candidate in computer-aided drug design?
The drug-discovery process is highly costly and time-consuming. Thus, computer-aided drug design has become a very popular field and got applications. As the drug is used in human subjects, the protocol/technique/procedure to drug-design should be highly generalized and comprehensive. Generally high docking-scored drugs are considered best drug-candidates. I guess we should also check whether the best-scored drug satisfies any of the ADMET parameters. I think the optimum scored drug is...
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1 Answer 0 Votes
How can AI-based movement monitoring support rehabilitation after hip fracture without compromising older adults’ autonomy and person-centred care?
I am developing a doctoral research direction involving AI-assisted movement monitoring for older adults recovering after hip fracture. The intended role is to identify movement patterns or fall-risk indicators and support timely, individualized rehabilitation—not to replace clinical judgment or human interaction. What design features and outcome measures would best demonstrate that such a system is clinically useful, acceptable to older adults, and ethically implemented? I am particularly...
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18 Answers 12 Votes
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13 Answers 0 Votes
The motivation behind conducting a risk assessment
Hello, I understand the purpose of a chemical risk assessment (e.g., setting safe exposure limits). However, I am wondering, in practical terms, what (aside from regulations) causes agencies to conduct these assessments. Consumer concerns? Potential litigation? Political pressure? In other words, what signals do the EPA and other regulatory agencies get that convinces them to conduct an assessment? Thank you.
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