The first question as expressed, is a general one, but there is ample evidence in experimental animals that in utero exposure to genotoxic carcinogens can cause cancer in offspring. There is certainly evidence in humans that maternal exposure to certain chemicals can lead to permanent damage in offspring, such as, in the cases of ethanol, thalidomide, and DES. The effects of these compounds may not result from genotoxicity, but they illustrate that chemicals with a wide variety of physico-chemical properties can pass from pregnant woman to fetus. There seems to be no obvious reason why 1,3D should be an exception.
No, unless a repeat somatic cell clastogenicity test would lead to a clear pos response. There are no described cases for a germ cell only mutagen
This cannot be excluded. Concerning the in vitro tests for genotoxic effects of 1,3-D, I would strongly recommend the performance of a robust in vitro micronucleus test in human lymphocytes (OECD TG 487).