8.4
SciPi 145: Peer review of the genotoxicity, toxicokinetics, and carcinogenicity of a pesticide
Should 1,3-D be tested in non-human primates?
Results
(3 Answers)
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Expert 9
I would not recommend testing 1,3-D in NHP's. A primate study would be impractical in cost and time to completion because of the much longer life span of primates while still not providing a definitive answer to the question.
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Expert 11
No, regarding tumor endpoints, such studies are not helpful due to low numbers/group and duration required.
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Expert 6
No, I do not think that it is necessary to test 1,3-D in non human primates.
Expert 11
04/18/2019 05:32Guess that there is agreement here and no need for debate ?
Expert 7
04/18/2019 08:28Yes, not necessary. And agree with comments on practicalities as well as ethical considerations given current directions to reduce animal usage.
Expert 6
04/18/2019 15:06Yes, everyone agrees that test in non human primates is not necessary.
Expert 9
04/18/2019 20:53It seems that we all agree that a primate study is not warranted.