In your opinion, what are the strengths of Key Characteristics (Select all that apply)

Answer Explanations

• Helpful in organizing mechanistic data

  user-957551

  Other than utility for organizing mechanistic data, human (or any organismal) variability in combination with exposure potential defines the ultimate outcome of observable physiological effects. Thus, KC may not be predictive until the actual exposure is known.

• Take into account a wide range of mechanistic data (e.g., QSAR, in vitro, in vivo and epidemiological/clinical) Quantitative

  user-532952

  They sort out nomenclature for aspects related to risk/hazard assessment that are sometimes difficult to compare statistically

• Easy to understand Easy to use (e.g., fewer KCs than Key Events [KEs]) Helpful in organizing mechanistic data

  user-390626

  Primarily a categorical tool for describing basic bimolecular attributes of a compound in relation to general outcomes.